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Medications like lubiprostone or linaclotide specifically increase intestinal fluid secretion and muscle contractions, addressing the underlying mechanism of tirzepatide-related constipation

"Lipotoxicity plays a key role in the development of both insulin resistance and muscle atrophy in patients with type 2 diabetes." Obesity Reviews 20.9 (2019): 1205-1217

Semaglutide medications are still the most popular weight loss medication to prescribe with 82% reporting they actively prescribe Ozempic, 65% reporting they actively prescribe Wegovy, and 37% prescribing Rybelsus

It is under study for potential treatment of microclots and lung damage due to COVID-19 infection